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Mastino Rescue, Inc. is breed-specific to the magnificent Neapolitan Mastiff, and we operate in most States within the USA

Mastino Rescue, Inc. is a nationwide, registered 501(c)(3) non-profit organization, dedicated to rescuing and rehoming Neapolitan Mastiffs in need, throughout the USA. We are all volunteers (none of us gets paid for what we do), and we are ALWAYS in need of guardian breed-experienced volunteers, fosters, and families who are interested in adopting a Neapolitan Mastiff! 

Over the last decade, Neapolitan Mastiffs have become more popular in the United States. Along with their increased popularity,  it has become quite common for Neapolitan Mastiffs to end up in kill shelters, and we also have a constant flow of owner surrender requests.  Neapolitan Mastiffs are truly amazing dogs, but they are not a good fit for the inexperienced dog owner. Please make sure to do plenty of research before deciding to add a Neapolitan Mastiff to your family. If you've already done so, and you're interested in adopting, you have come to the right place, so please take the first step and submit an application!



Highlighted Dogs
See all the Dogs!
  Fiona (MEDICAL HOLD)
Fiona is a 5 and 1/2-year old Neapolitan Mastiff, currently being fostered in St. Louis, MO.  Our sweet senior girl is presently in poor medical shape.  We found out that she is high heart...read more about Fiona (MEDICAL HOLD)
  Giordano
GIORDANO is ADOPTABLE in NORTHERN CA! Giordano is a 3.5-year old male Neapolitan Mastiff, and he is a BIG boy, weighing about 160#.  Gio lived his entire previous life as an outside dog, and...read more about Giordano
  Nerina (MEDICAL HOLD)
Nerina was pulled on 6/29/20 from a kill shelter in Texas.  Stay tuned for more information. 
  Agnese
Our beautiful blue fawn brindle Agnese which is Italian for Agnes is ready for her forever home.  Thanks to our wonderful fosters Bill and Anne in North Carolina that have decompressed and evalua...read more about Agnese
  Bianca
Bianca is a 3-year old Neapolitan Mastiff, and she was surrendered to our rescue, along with her sister, Bambi, when their owner could no longer care for them. Bianca and Bambi previously&nb...read more about Bianca
  Bambi
Bambi is a 3-year old Neapolitan Mastiff, and she was surrendered to our rescue, along with her sister, Bianca, when their owner could no longer care for them. Bambi and Bianca previously&nb...read more about Bambi

201 Carmel Woods Dr. •  Ellisville, MO 63021  •  mastinorescue [ at ] gmail.com